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A liver metastasis is a malignant tumor in the liver that has spread from another organ affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary tumors. In 50% of all cases the primary tumor is of the gastrointestinal tract, other common sites include the breast, ovaries, bronchus and kidney. Tumor emboli entering the sinusoids through the liver blood supply appear to be physically obstructed by the Kupffer cells, but if tumor emboli are larger, they tend to become lodged in the portal venous branches. == Features == * Hepatomegaly - with a nodular free edge of liver * Tenderness * Cachexic * Ascites * Jaundice * Pyrexia - up to 10% of patients * Alkaline Phosphatase (ALP) and gamma glutamyl transpeptidase (GGT) elevated * Ultrasound scan and CT scan - multiple filling defects. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Metastatic liver disease」の詳細全文を読む スポンサード リンク
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